Morton are once again missing injured trio David MacGregor, Darren Young and Kevin Kelbie.
The Greenock side are on a run of four matches without defeat and are three points ahead of the hosts.
Queen of the South manager Kenny Brannigan: "It would be great to have both these guys available (Reid & Burns) as we all need a boost after losing to Dundee at the weekend.
"The effort was great but not much else was.
"Our last victory over Morton was a great 4-0 win, however I would gladly settle for a 1-0 win to get us going again."
Morton manager Allan Moore: "We managed to get a great result at Dunfermline and kick-off could not come quick enough for the Stirling game and then of course the snow came and Saturday's game was called off.
"We need to use that frustration positively against Queen of the South and of course defend better than we did when we played them at our place as we let David Weatherston's pace win the game."
Source: BBC Sport
Source: BBC Sport