Morton will list the same squad that defeated Cowdenbeath last weekend against Raith if defender Jason Naismith overcomes a blow to the head and Peter Weatherston shakes off a calf problem.
Martin Hardie and Kevin Rutkiewicz have returned to training, but this game has come too soon for them and they will miss out, as will Peter MacDonald.
The Greenock men have won their last two games and manager Allan Moore is determined they go chasing a hat-trick.
He said: "We can improve our position in the table by at least one place if we win so we have to keep the run going.
"Our former player Brian Graham is scoring a lot of goals, so he'll need to be watched closely."
Raith's only doubt is striker Pat Clarke who has been troubled by a calf injury.
The Stark's Park side face Celtic on Tuesday night in a Scottish Communities League Cup tie, but have been told to put that out of their minds by boss Grant Murray.
Murray said: "We cannot go there thinking about Celtic as Morton have won their last two games and will be really keen to get a third success.
"We bounced back last week to defeat Airdrie after a couple of disappointing results so we're going there in very good spirits.
"We won at Cappielow on the final day of last season and a repeat of that would be fantastic."